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KMID : 0361020110540110741
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Korean Journal of Otolaryngology - Head and Neck Surgery
2011 Volume.54 No. 11 p.741 ~ p.745
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Salivary Diagnostics
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Kim Jeong-Kyu
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Abstract
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Saliva contains various sources of biomarkers like protein, mRNA, microRNA, metabolites and microbiota that could be considered as diagnostic alphabets. Collection of saliva is safe, easy, and non-invasive for both patients and medical workers. For the past 20 years, salivary diagnostics have been developed to monitor oral diseases. Recently, salivary diagnostics have extended the range of application from oral cavity to systemic sites such as pancreatic cancer and diabetes. Establishment of definitive salivary biomarkers for different diseases and development of accurate, easy-to-use and portable detection devices are required for the real clinical application of salivary diagnostics in the future medical practice.
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KEYWORD
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Saliva, Biomarkers, Diagnosis, Oral cancer
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